Initializing

Gaining access to millions of annotated cells across 10+ cancer indications.

Analyzing pathology slides

Our algorithms detect and characterize tissue and cell architecture.

Calculating Features

Cell & area locations are intersected to compute over hundreds of complex feature values.

Predicting Response

Deep-learning models combining spatial features and clinical data drive the discovery of pathology based spatial biomarkers.

Initializing

Gaining access to millions of annotated cells across 10+ cancer indications.

Analyzing pathology slides

Our algorithms detect and characterize tissue and cell architecture.

Calculating Features

Cell & area locations are intersected to compute over hundreds of complex feature values.

Predicting Response

Deep-learning models combining spatial features and clinical data drive the discovery of pathology based spatial biomarkers.

PRODUCTS

Our Offering

ABOUT US

We are transforming precision medicine with AI-powered pathology

Our team’s work is a unique collaboration of experienced AI technologists, physicians and exceptional healthcare research professionals.

Exploratory Research Platform

Our Platform empowers researchers to discover novel, human interpretable pathology-based biomarkers that predict response to therapy, identify genomic markers or explain complex biological phenomena at scale.

AI-Powered Clinical Trial Assays

Qualified biomarkers are incorporated into prospective clinical trials via Nucleai’s AI-powered digital assays. In partnership with CROs and central laboratories, we support a compliant (FDA, CLIA, GxP) and scalable patient selection process.

Companion Diagnostics Development

In partnership with biopharma, diagnostics and clinical laboratories, we develop and deploy Nucleai’s digital assays as companion diagnostics across the world, providing physicians with the best diagnostic tools to improve patient lives.

Our Platform

Nucleai’s platform unlocks spatial insights. In Nucleai Atom, your pathology slides are transformed into raw data of cell and area locations. The raw data is fed into the Nucleai engine, computing hundreds of spatial features intersected with outcome to predict drug response.

DATA & INSTITUTIONAL PARTNERS

INVESTORS

SCIENTIFIC PUBLICATIONS

LEADERSHIP

CAREERS

Join Us in Biomarker Discovery

At Nucleai, we bring physicians and researchers cutting edge AI-based technology that identifies pathology-based biomarkers that can predict response to therapy and significantly improve patient outcomes. Come join our team of experienced AI engineers, world renowned clinicians, and others, to revolutionize precision medicine and make a major impact.
Data Operations Team Leader

Data Operations Team Leader

Tel Aviv

Full-Stack Software Engineer

Full-Stack Software Engineer

Tel Aviv

Medical Data Specialist Full Time

Medical Data Specialist Full Time

Tel Aviv

Product Marketing Manager

Product Marketing Manager

Tel Aviv

Senior Full-stack Software Engineer

Senior Full-stack Software Engineer

Tel Aviv

Solutions Architect (Life Sciences) - United States

Solutions Architect (Life Sciences) - United States

United States

NEWS & UPDATES

Nucleai Launches New Multiplex Imaging Spatial Analysis Solution to Increase Reliability and Speed of Immunofluorescence Analysis for Drug Discovery and Development

Nucleai, a leader in AI-powered spatial biology, today announced the expansion of its spatial biology platform to include a new generation of multiplex immunofluorescence (mIF) analysis that uses deep learning to establish new levels of accuracy, speed, and generalizability, further unlocking the power of mIF data for drug discovery and development. Nucleai will present new […]

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Nucleai Hopes to Engage Pharma on Next-Gen Immunotherapies With Proof-of-Concept AI-Based Biomarker

NEW YORK –Nucleai researchers investigated whether, by using spatial biology to analyze interactions between the immune system and tumor microenvironment, it is possible to find biomarkers predictive of sensitivity to immuno-oncology drugs. In a retrospective multi-center study conducted in the US and Israel, where the firm is based, Nucleai analyzed biopsy slides and clinical outcomes […]

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Israel: An Untapped Biotech Investment Opportunity

With military precision and academic ingenuity, Israel is building a thriving biotech ecosystem on the heels of a renowned high-tech industry. Much more than just the iconic Teva Pharmaceuticals, venture capitalists would do well to pay attention to the innovation stemming from this largely unmined investment opportunity. “Everything about it is about innovation,” said Michael […]

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Nucleai, Propath Partnership Paves Way for Spatial Oncology Biomarkers

Spatial biology specialists Nucleai and Propath UK have announced a partnership to develop and validate an immunofluorescence assay focused on 30 immuno-oncology protein targets that could inform the development of novel oncology biomarkers and companion diagnostics. Dr Ken Bloom, head of Pathology at Nucleai, explained that spatial biology—the study of tissues within their multidimensional context—“is considered a new frontier and […]

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Nucleai and Propath UK announce partnership for end-to-end AI-powered spatial analysis of a 30-plex immunofluorescence immuno-oncology panel

Propath UK, Europe’s leading CRO for spatial biology, and Nucleai, a leader in AI-powered spatial biology transforming precision medicine by unlocking spatial biology insights from pathology data, announce their collaboration to develop and validate a 30-plex immunofluorescence (IF) panel focused on protein targets relevant to immuno-oncology. For our pharmaceutical and biotechnology partners, this groundbreaking panel, in […]

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